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Dihydroergotoxine MeSH Descriptor Data 2022


MeSH Heading
Dihydroergotoxine
Tree Number(s)
D03.132.327.412.250
D03.633.400.562.400
Unique ID
D004088
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004088
Scope Note
A mixture of three different hydrogenated derivatives of ERGOTAMINE: DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and DIHYDROERGOCRYPTINE. Dihydroergotoxine has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. The methanesulfonate salts of this mixture of alkaloids are called ERGOLOID MESYLATES.
Entry Term(s)
Co-Dergocrine
Dihydroergotoxin
Ergot Alkaloids, Hydrogenated
Pharm Action
Adrenergic alpha-Antagonists
Dopamine Agonists
Registry Number
11032-41-0
CAS Type 1 Name
Ergotoxine, dihydro-
Previous Indexing
Ergot Mesylates (1973-1974)
See Also
Dihydroergocornine
Dihydroergocristine
Dihydroergocryptine
Public MeSH Note
1977; see ERGOT ALKALOIDS HYDROGENATED 1975-1976; for ERGOT ALKALOIDS, HYDROGENATED see ERGOLOID MESYLATES 1992-2001
History Note
1977(1975); for ERGOT ALKALOIDS, HYDROGENATED use ERGOLOID MESYLATES 1992-2001
Date Established
1977/01/01
Date of Entry
1974/11/27
Revision Date
2016/05/31
Dihydroergotoxine Preferred
Ergot Alkaloids, Hydrogenated Broader
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