MeSH Browser

MeSH Heading: Dihydroergotoxine
Tree Number(s): D03.132.327.412.250; D03.633.400.562.400
Unique ID: D004088
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004088
Scope Note: A mixture of three different hydrogenated derivatives of ERGOTAMINE: DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and DIHYDROERGOCRYPTINE. Dihydroergotoxine has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. The methanesulfonate salts of this mixture of alkaloids are called ERGOLOID MESYLATES.
Entry Term(s): Co-Dergocrine; Dihydroergotoxin; Ergot Alkaloids, Hydrogenated
Pharm Action: Adrenergic alpha-Antagonists
Dopamine Agonists
Registry Numbers: 11032-41-0; 0
CAS Type 1 Name: Ergotoxine, dihydro-
Previous Indexing: Ergot Mesylates (1973-1974)
See Also: Dihydroergocornine; Dihydroergocristine; Dihydroergocryptine
Public MeSH Note: 1977; see ERGOT ALKALOIDS HYDROGENATED 1975-1976; for ERGOT ALKALOIDS, HYDROGENATED see ERGOLOID MESYLATES 1992-2001
History Note: 1977(1975); for ERGOT ALKALOIDS, HYDROGENATED use ERGOLOID MESYLATES 1992-2001
Date Established: 1977/01/01
Date of Entry: 1974/11/27
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0006406
Registry Numbers: 11032-41-0
Scope Note: A mixture of three different hydrogenated derivatives of ERGOTAMINE: DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and DIHYDROERGOCRYPTINE. Dihydroergotoxine has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. The methanesulfonate salts of this mixture of alkaloids are called ERGOLOID MESYLATES.
Terms: Dihydroergotoxine Preferred Term
Term UI T012400
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Co-Dergocrine
Term UI T012399
Date03/14/1991
LexicalTag NON
ThesaurusID NLM (1992); Dihydroergotoxin
Term UI T012401
Date05/28/1976
LexicalTag NON
ThesaurusID UNK (19XX)

Dihydroergotoxine MeSH Descriptor Data 2025