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Encephalomalacia MeSH Descriptor Data 2025


MeSH Heading
Encephalomalacia
Tree Number(s)
C10.228.140.461
Unique ID
D004678
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004678
Scope Note
Softening or loss of brain tissue following CEREBRAL INFARCTION; cerebral ischemia (see BRAIN ISCHEMIA), infection, CRANIOCEREBRAL TRAUMA, or other injury. The term is often used during gross pathologic inspection to describe blurred cortical margins and decreased consistency of brain tissue following infarction. Multicystic encephalomalacia refers to the formation of multiple cystic cavities of various sizes in the cerebral cortex of neonates and infants following injury, most notably perinatal hypoxia-ischemic events. (From Davis et al., Textbook of Neuropathology, 2nd ed, p665; J Neuropathol Exp Neurol, 1995 Mar;54(2):268-75)
Entry Term(s)
Cerebromalacia
Encephalomalacia, Multicystic
Multicystic Encephalomalacia
NLM Classification #
WL 348
Public MeSH Note
1966
History Note
1966(1964)
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2001/07/25
Encephalomalacia Preferred
Multicystic Encephalomalacia Narrower
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