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Genes, Lethal MeSH Descriptor Data 2022


MeSH Heading
Genes, Lethal
Tree Number(s)
G05.360.340.024.340.350
Unique ID
D005804
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D005804
Scope Note
Genes whose loss of function or gain of function MUTATION leads to the death of the carrier prior to maturity. They may be essential genes (GENES, ESSENTIAL) required for viability, or genes which cause a block of function of an essential gene at a time when the essential gene function is required for viability.
Entry Term(s)
Alleles, Lethal
Previous Indexing
Genes (1966-1967)
See Also
Synthetic Lethal Mutations
Public MeSH Note
68
History Note
68
Date Established
1968/01/01
Date of Entry
1999/01/01
Revision Date
2016/06/30
Genes, Lethal Preferred
Alleles, Lethal Narrower
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