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Synthetic Lethal Mutations
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Synthetic Lethal Mutations
Tree Number(s)
G05.365.590.917
Unique ID
D000072020
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000072020
Scope Note
Mutations in genes which lead to cell or organism death when occurring in combination with mutations in one or more other genes.
Entry Term(s)
Synthetic Lethal Mutation
Synthetic Lethality
See Also
Genes, Lethal
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/07/01
Allowable Qualifiers
drug effects (DE)
genetics (GE)
immunology (IM)
physiology (PH)
radiation effects (RE)
Genetic Phenomena [G05]
Genetic Variation [G05.365]
Mutation [G05.365.590]
Allelic Imbalance [G05.365.590.029]
Base Pair Mismatch [G05.365.590.060]
Chromosome Aberrations [G05.365.590.175]
Codon, Nonsense [G05.365.590.195]
DNA Repeat Expansion [G05.365.590.220]
Frameshift Mutation [G05.365.590.265]
Gain of Function Mutation [G05.365.590.288]
Gene Amplification [G05.365.590.310]
Gene Duplication [G05.365.590.320]
Genomic Instability [G05.365.590.335]
Germ-Line Mutation [G05.365.590.350]
INDEL Mutation [G05.365.590.500]
Loss of Function Mutation [G05.365.590.538]
Mutagenesis, Insertional [G05.365.590.575]
Mutation Accumulation [G05.365.590.594]
Mutation Rate [G05.365.590.612]
Mutation, Missense [G05.365.590.650]
Point Mutation [G05.365.590.675]
Sequence Deletion [G05.365.590.762]
Sequence Inversion [G05.365.590.770]
Silent Mutation [G05.365.590.803]
Suppression, Genetic [G05.365.590.835]
Synthetic Lethal Mutations [G05.365.590.917]
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Synthetic Lethal Mutations
Preferred
Concept UI
M000616244
Scope Note
Mutations in genes which lead to cell or organism death when occurring in combination with mutations in one or more other genes.
Terms
Synthetic Lethal Mutations
Preferred Term
Term UI
T000902169
Date
06/01/2016
LexicalTag
NON
ThesaurusID
NLM (2017)
Synthetic Lethal Mutation
Term UI
T000902168
Date
06/01/2016
LexicalTag
NON
ThesaurusID
NLM (2017)
Synthetic Lethality
Related
Concept UI
M000616245
Terms
Synthetic Lethality
Preferred Term
Term UI
T000897877
Date
03/29/2016
LexicalTag
NON
ThesaurusID
NLM (2017)
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