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Frameshift Mutation MeSH Descriptor Data 2022


MeSH Heading
Frameshift Mutation
Tree Number(s)
G05.365.590.265
Unique ID
D016368
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016368
Annotation
do not confuse with FRAMESHIFTING, RIBOSOMAL, physiology process & form of genetic translation; do not confuse effects of drug & radiation on frameshift mutation with drug- & radiation-induced frameshift mutation
Scope Note
A type of mutation in which a number of NUCLEOTIDES deleted from or inserted into a protein coding sequence is not divisible by three, thereby causing an alteration in the READING FRAMES of the entire coding sequence downstream of the mutation. These mutations may be induced by certain types of MUTAGENS or may occur spontaneously.
Entry Term(s)
Frame Shift Mutation
Mutation, Frameshift
Out-of-Frame Deletion
Out-of-Frame Insertion
Out-of-Frame Mutation
Previous Indexing
Mutation (1968-1990)
Public MeSH Note
91
History Note
91
Date Established
1991/01/01
Date of Entry
1990/05/25
Revision Date
2008/07/08
Frameshift Mutation Preferred
Out-of-Frame Insertion Narrower
Out-of-Frame Deletion Narrower
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