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Glucosylceramidase MeSH Descriptor Data 2022


MeSH Heading
Glucosylceramidase
Tree Number(s)
D08.811.277.450.420.412
Unique ID
D005962
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D005962
Annotation
/defic: consider also GAUCHER DISEASE
Scope Note
A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45.
Entry Term(s)
Acid beta-Glucosidase
Glucocerebrosidase
Glucocerebroside beta-Glucosidase
Glucosyl Ceramidase
Glucosylceramide beta-Glucosidase
Glucosylsphingosine Glucosyl Hydrolase
beta-Glucocerebrosidase
Registry Number
EC 3.2.1.45
CAS Type 1 Name
D-Glucosyl-N-acylsphingosine glucosylhydrolase
Previous Indexing
Cerebrosides (1970-1974)
Glucose (1970-1974)
Glycoside Hydrolases (1970-1974)
See Also
Gaucher Disease
Public MeSH Note
91; was see under GLUCOSIDASES 1975-90
History Note
91(75); was see under GLUCOSIDASES 1975-90
Date Established
1991/01/01
Date of Entry
1974/11/19
Revision Date
2013/07/08
Glucosylceramidase Preferred
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