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Glutamate Decarboxylase MeSH Descriptor Data 2024

MeSH Heading
Glutamate Decarboxylase
Tree Number(s)
Unique ID
RDF Unique Identifier
Scope Note
A pyridoxal-phosphate protein that catalyzes the alpha-decarboxylation of L-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The enzyme is found in bacteria and in invertebrate and vertebrate nervous systems. It is the rate-limiting enzyme in determining GAMMA-AMINOBUTYRIC ACID levels in normal nervous tissues. The brain enzyme also acts on L-cysteate, L-cysteine sulfinate, and L-aspartate. EC
Entry Term(s)
Glutamate Carboxy-Lyase
Glutamic Acid Decarboxylase
CAS Type 1 Name
Previous Indexing
Carboxy-Lyases (1973-1974)
Glutamates (1973-1974)
Public MeSH Note
84; was see under CARBOXY-LYASES 1975-83
History Note
84(75); was see under CARBOXY-LYASES 1975-83
Date Established
Date of Entry
Revision Date
Glutamate Decarboxylase Preferred
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