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Pyruvate Decarboxylase MeSH Descriptor Data 2025


MeSH Heading
Pyruvate Decarboxylase
Tree Number(s)
D08.811.520.224.125.750
Unique ID
D011767
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011767
Scope Note
Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC 4.1.1.1.
Entry Term(s)
2-Oxo Acid Carboxy-Lyase
Pyruvic Decarboxylase
alpha-Carboxylase
alpha-Ketoacid Carboxylase
Registry Numbers
EC 4.1.1.1
Related Numbers
9001-04-1
Previous Indexing
Carboxy-Lyases (1973-1974)
Pyruvates (1973-1974)
Public MeSH Note
91; was see under CARBOXY-LYASES 1975-90
History Note
91(75); was see under CARBOXY-LYASES 1975-90
Date Established
1991/01/01
Date of Entry
1974/11/19
Revision Date
2003/07/09
Pyruvate Decarboxylase Preferred
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