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Histamine H1 Antagonists MeSH Descriptor Data 2022


MeSH Heading
Histamine H1 Antagonists
Tree Number(s)
D27.505.519.625.375.425.400
D27.505.696.577.375.425.400
Unique ID
D006634
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D006634
Annotation
HISTAMINE H1 ANTAGONISTS, NON-SEDATING is also available
Scope Note
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.
Entry Version
HISTAMINE H1 ANTAG
Entry Term(s)
Antagonists, Histamine H1
Antagonists, Histamine H1 Receptor
Antihistamines, Classical
Antihistamines, Sedating
Antihistaminics, Classical
Antihistaminics, H1
Blockaders, Histamine H1 Receptor
First Generation H1 Antagonists
H1 Receptor Blockaders
Histamine H1 Antagonist
Histamine H1 Blockers
Histamine H1 Receptor Antagonist
Histamine H1 Receptor Antagonists
Histamine H1 Receptor Blockaders
Receptor Blockaders, H1
Registry Number
0
NLM Classification #
QV 157
See Also
Anti-Allergic Agents
Bronchodilator Agents
Hypersensitivity, Immediate
Public MeSH Note
95; was HISTAMINE H1 RECEPTOR BLOCKADERS 1977-94; was ANTIHISTAMINICS 1963-76; ANTIHISTAMINICS, CLASSICAL was ANTIHISTAMINICS see HISTAMINE H1 RECEPTOR BLOCKADERS 1977-90
Online Note
use HISTAMINE H1 ANTAGONISTS to search HISTAMINE H1 RECEPTOR BLOCKADERS 1977-94 and ANTIHISTAMINICS 1966-76
History Note
95; was HISTAMINE H1 RECEPTOR BLOCKADERS 1977-94; was ANTIHISTAMINICS 1963-76; ANTIHISTAMINICS, CLASSICAL was ANTIHISTAMINICS see HISTAMINE H1 RECEPTOR BLOCKADERS 1977-90
Date Established
1977/01/01
Date of Entry
1976/05/05
Revision Date
2021/06/30
Histamine H1 Antagonists Preferred
Antihistamines, Classical Narrower
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