Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

17-alpha-Hydroxypregnenolone MeSH Descriptor Data 2025


MeSH Heading
17-alpha-Hydroxypregnenolone
Tree Number(s)
D04.210.500.745.745.725.395
D06.472.040.585.745.500
D06.472.334.851.687.500.500
Unique ID
D006907
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D006907
Scope Note
A 21-carbon steroid that is converted from PREGNENOLONE by STEROID 17-ALPHA-HYDROXYLASE. It is an intermediate in the delta-5 pathway of biosynthesis of GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.
Entry Term(s)
17 alpha-Hydroxypregnenolone
17-Hydroxypregnenolone
17-Hydroxypregnenolone, (3alpha)-Isomer
17-Hydroxypregnenolone, (3beta,13alpha)-Isomer
17-Hydroxypregnenolone, (3beta,13alpha,17alpha)-Isomer
17-Hydroxypregnenolone, (3beta,17alpha)-Isomer
17alpha-Hydroxypregnenolone
Hydroxypregnenolone
Registry Numbers
387-79-1
1887-95-2
33999-97-2
Related Numbers
1887-95-2
19454-90-1
33999-90-5
33999-97-2
CAS Type 1 Name
Pregn-5-en-20-one, 3,17-dihydroxy-, (3beta)-
Public MeSH Note
2004; see HYDROXYPREGNENOLONE 1972-2003; 17-HYDROXYPREGNENOLONE was indexed under HYDROXYPREGNENOLONE (NM) 1981-2003
History Note
2004 (1964); for 17-HYDROXYPREGNENOLONE use HYDROXYPREGNENOLONE (NM) 1981-2003
Date Established
1972/01/01
Date of Entry
1999/01/01
Revision Date
2016/05/27
17-alpha-Hydroxypregnenolone Preferred
17-Hydroxypregnenolone, (3alpha)-Isomer Related
17-Hydroxypregnenolone, (3beta,13alpha,17alpha)-Isomer Narrower
page delivered in 0.13s