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Iduronate Sulfatase MeSH Descriptor Data 2022


MeSH Heading
Iduronate Sulfatase
Tree Number(s)
D08.811.277.352.827.500
Unique ID
D007066
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007066
Scope Note
An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency has been demonstrated in Hunter's syndrome, which is characterized by an excess of dermatan sulfate and heparan sulfate. EC 3.1.6.13.
Entry Term(s)
Hunter Corrective Factor
Iduronate Sulfate Sulfatase
Iduronatesulfate Sulfohydrolase
Sulfoiduronate Sulfatase
Registry Number
EC 3.1.6.13
CAS Type 1 Name
L-Iduronate-2-sulfate 2-sulfohydrolase
Previous Indexing
Iduronic Acid (1975)
Sulfatases (1972-1975)
Uronic Acids (1972-1975)
See Also
Mucopolysaccharidosis II
Public MeSH Note
91; was see under SULFATASES 1976-90
History Note
91(76); was see under SULFATASES 1976-90
Entry Combination
deficiency:Mucopolysaccharidosis II
Date Established
1991/01/01
Date of Entry
1975/07/25
Revision Date
2009/07/06
Iduronate Sulfatase Preferred
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