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Mucopolysaccharidosis II MeSH Descriptor Data 2022


MeSH Heading
Mucopolysaccharidosis II
Tree Number(s)
C10.597.606.360.455.750
C16.320.322.500.750
C16.320.400.525.750
C16.320.565.202.715.645
C16.320.565.595.600.645
C17.300.550.575.645
C18.452.648.202.715.645
C18.452.648.595.600.645
Unique ID
D016532
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016532
Scope Note
Systemic lysosomal storage disease marked by progressive physical deterioration and caused by a deficiency of L-sulfoiduronate sulfatase. This disease differs from MUCOPOLYSACCHARIDOSIS I by slower progression, lack of corneal clouding, and X-linked rather than autosomal recessive inheritance. The mild form produces near-normal intelligence and life span. The severe form usually causes death by age 15.
Entry Version
MPS II
Entry Term(s)
Gargoylism, Hunter Syndrome
Hunter Syndrome
Hunter Syndrome Gargoylism
Hunter's Syndrome
I2S Deficiency
Iduronate 2-Sulfatase Deficiency
Iduronate Sulfatase Deficiency
Mucopolysaccharidosis 2
Mucopolysaccharidosis Type 2
Mucopolysaccharidosis Type II
Sulfoiduronate Sulfatase Deficiency
Previous Indexing
Mucopolysaccharidosis I (1966-1991)
See Also
Iduronate Sulfatase
Mucopolysaccharidosis I
Public MeSH Note
1992; for MUCOPOLYSACCHARIDOSIS 2 and HUNTER'S SYNDROME see LIPOCHONDRODYSTROPHY 1976-1991
History Note
1992; for MUCOPOLYSACCHARIDOSIS 2 and HUNTER'S SYNDROME use LIPOCHONDRODYSTROPHY 1976-1991
Date Established
1992/01/01
Date of Entry
1991/06/21
Revision Date
2018/07/01
Mucopolysaccharidosis II Preferred
Sulfoiduronate Sulfatase Deficiency Related
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