MeSH Browser

MeSH Heading: Isoleucine-tRNA Ligase
Tree Number(s): D08.811.464.263.200.450
Unique ID: D007533
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007533
Scope Note: An enzyme that activates isoleucine with its specific transfer RNA. EC 6.1.1.5.
Entry Term(s): Ile-tRNA Ligase; Isoleucyl T RNA Synthetase; Isoleucyl- tRNA Synthetase ILS1; Isoleucyl-tRNA Synthetase; Isoleucyl-tRNA Synthetase 1; Isoleucyl-tRNA Synthetase ILES1
Registry Numbers: EC 6.1.1.5; 0
CAS Type 1 Name: L-Isoleucine:tRNA(Ile) ligase (AMP-forming)
Previous Indexing: Amino Acyl T RNA Synthetases (1972-1974); Isoleucine (1972-1974)
Public MeSH Note: 1998; see ISOLEUCYL TRNA SYNTHETASE 1991-1997; see AMINO ACYL TRNA SYNTHETASES 1975-1990
History Note: 1998(1975)
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2021/07/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0011767
Registry Numbers: EC 6.1.1.5
Scope Note: An enzyme that activates isoleucine with its specific transfer RNA. EC 6.1.1.5.
Terms: Isoleucine-tRNA Ligase Preferred Term
Term UI T022645
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1975); Isoleucyl T RNA Synthetase
Term UI T022644
Date11/05/1996
LexicalTag NON
ThesaurusID NLM (1998); Ile-tRNA Ligase
Term UI T409483
Date03/16/2000
LexicalTag NON
ThesaurusID NLM (2001); Isoleucyl-tRNA Synthetase
Term UI T409484
Date03/16/2000
LexicalTag NON
ThesaurusID NLM (2001); Isoleucyl-tRNA Synthetase 1
Term UI T001107466
Date06/03/2021
LexicalTag NON
ThesaurusID NLM (2022); Isoleucyl-tRNA Synthetase ILES1
Term UI T001107467
Date06/03/2021
LexicalTag NON
ThesaurusID NLM (2022)

Isoleucine-tRNA Ligase MeSH Descriptor Data 2025