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Mink Cell Focus-Inducing Viruses MeSH Descriptor Data 2025
Strains of MURINE LEUKEMIA VIRUS discovered in 1976 by Hartley, Wolford, Old, and Rowe and so named because the viruses originally isolated had the capacity to transform cell foci in mink cell cultures. MCF viruses are generated by recombination with ecotropic murine leukemia viruses including AKR, Friend, Moloney, and Rauscher, causing ERYTHROLEUKEMIA and severe anemia in mice.
Entry Term(s)
MCF Viruses
Mink cell focus-inducing virus
Registry Numbers
txid11785
Previous Indexing
Friend Virus (1966-1985)
Leukemia, Experimental (1966-1985)
Mouse Leukemia Viruses (1966-1985)
Public MeSH Note
91; was see under MOUSE LEUKEMIA VIRUSES 1986-90
History Note
91(86); was see under MOUSE LEUKEMIA VIRUSES 1986-90
Strains of MURINE LEUKEMIA VIRUS discovered in 1976 by Hartley, Wolford, Old, and Rowe and so named because the viruses originally isolated had the capacity to transform cell foci in mink cell cultures. MCF viruses are generated by recombination with ecotropic murine leukemia viruses including AKR, Friend, Moloney, and Rauscher, causing ERYTHROLEUKEMIA and severe anemia in mice.