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Neurofibroma MeSH Descriptor Data 2022


MeSH Heading
Neurofibroma
Tree Number(s)
C04.557.580.600.580
C10.551.775.500.750
C10.668.829.725.500.600
Unique ID
D009455
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D009455
Annotation
solitary; multiple = NEUROFIBROMATOSES but see MeSH definition; coord IM with precoord organ/neopl term (IM)
Scope Note
A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2009/07/06
Neurofibroma Preferred
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