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Ochronosis MeSH Descriptor Data 2025


MeSH Heading
Ochronosis
Tree Number(s)
C23.550.744
Unique ID
D009794
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D009794
Scope Note
The yellowish discoloration of connective tissue due to deposition of HOMOGENTISIC ACID (a brown-black pigment). This is due to defects in the metabolism of PHENYLALANINE and TYROSINE. Ochronosis occurs in ALKAPTONURIA, but has also been associated with exposure to certain chemicals (e.g., PHENOL, trinitrophenol, BENZENE DERIVATIVES).
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2009/07/06
Ochronosis Preferred
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