MeSH Browser

MeSH Heading: Pentobarbital
Tree Number(s): D03.383.742.698.253.593
Unique ID: D010424
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010424
Scope Note: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
Entry Term(s): Diabutal; Etaminal; Ethaminal; Mebubarbital; Mebumal; Nembutal; Pentobarbital Sodium; Pentobarbital, Monosodium Salt; Pentobarbitone; Sagatal
Pharm Action: Adjuvants, Anesthesia
Hypnotics and Sedatives
GABA Modulators
Related Numbers: 57-33-0; 76-74-4; NJJ0475N0S
CAS Type 1 Name: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylbutyl)-
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0016182
Related Numbers: 57-33-0; 76-74-4; NJJ0475N0S
Scope Note: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
Terms: Pentobarbital Preferred Term
Term UI T030784
Date01/01/1999
LexicalTag NON
ThesaurusID; Mebubarbital
Term UI T030783
Date12/30/1976
LexicalTag NON
ThesaurusID; Pentobarbitone
Term UI T030785
Date08/01/1980
LexicalTag NON
ThesaurusID

Pentobarbital MeSH Descriptor Data 2024