MeSH Browser

MeSH Heading: Semustine
Tree Number(s): D02.065.950.594.440.700; D02.654.692.440.700
Unique ID: D012673
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D012673
Scope Note: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
Entry Term(s): Me-CCNU; MeCCNU; Methyl-CCNU; NSC-95441
Pharm Action: Antineoplastic Agents, Alkylating
CAS Type 1 Name: Urea, N-(2-chloroethyl)-N'-(4-methylcyclohexyl)-N-nitroso-
Previous Indexing: Cyclohexanes (1966-1974); Nitroso Compounds (1966-1972); Nitrosourea Compounds (1973-1974); Urea (1966-1972)
Public MeSH Note: 91; was see under NITROSOUREA COMPOUNDS 1975-90
History Note: 91(75); was see under NITROSOUREA COMPOUNDS 1975-90
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0019643
Scope Note: 4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
Terms: Semustine Preferred Term
Term UI T037483
Date01/01/1999
LexicalTag NON
ThesaurusID; Methyl-CCNU
Term UI T037481
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX); Me-CCNU
Term UI T037484
Date07/31/1980
LexicalTag NON
ThesaurusID UNK (19XX); MeCCNU
Term UI T037485
Date11/22/1994
LexicalTag NON
ThesaurusID NLM (1996)

Semustine MeSH Descriptor Data 2024