MeSH Browser

MeSH Heading: Sparsomycin
Tree Number(s): D03.383.742.698.715
Unique ID: D013033
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D013033
Annotation: an antineoplastic antibiotic
Scope Note: An antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems.
Pharm Action: Antibiotics, Antineoplastic
Protein Synthesis Inhibitors
Related Numbers: 1404-64-4
CAS Type 1 Name: 2-Propenamide, N-(1-(hydroxymethyl)-2-(((methylthio)methyl)sulfinyl)ethyl)-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinyl)-, (R-(R*,S*-(E)))-
Previous Indexing: Antibiotics (1974); Antibiotics, Antineoplastic (1974); Ribonucleosides (1974)
Public MeSH Note: 91; was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
History Note: 91(75); was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Sparsomycin MeSH Descriptor Data 2024