MeSH Browser

MeSH Heading: Lopinavir
Tree Number(s): D03.383.742.698.553
Unique ID: D061466
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D061466
Scope Note: An HIV protease inhibitor used in a fixed-dose combination with RITONAVIR. It is also an inhibitor of CYTOCHROME P-450 CYP3A.
Entry Term(s): A-157378.0; ABT 378; ABT-378; N-(4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pydrimidineacetamide
Pharm Action: HIV Protease Inhibitors
Cytochrome P-450 CYP3A Inhibitors
Public MeSH Note: 2012; LOPNAVIR was indexed under PYRIMIDINONES 2000-2011
History Note: 2012
Date Established: 2012/01/01
Date of Entry: 2011/06/27
Revision Date: 2016/07/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Lopinavir MeSH Descriptor Data 2024