HIV Protease Inhibitors MeSH Descriptor Data 2024

MeSH Heading: HIV Protease Inhibitors
Tree Number(s): D27.505.519.389.745.900.500; D27.505.954.122.388.077.088.420; D27.505.954.122.388.769.500
Unique ID: D017320
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017320
Scope Note: Inhibitors of HIV PROTEASE, an enzyme required for production of proteins needed for viral assembly.
Entry Version: HIV PROTEASE INHIB
Entry Term(s): HIV Protease Inhibitor
NLM Classification #: QV 268.5
Previous Indexing: Antiviral Agents (1990-1992); HIV Protease/antagonists & inhibitors (1990-1992)
Public MeSH Note: 93
History Note: 93
Date Established: 1993/01/01
Date of Entry: 1992/05/20
Revision Date: 2022/04/13

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Molecular Mechanisms of Pharmacological Action [D27.505.519]
    - Enzyme Inhibitors [D27.505.519.389]
      - Protease Inhibitors [D27.505.519.389.745]
        
        Viral Protease Inhibitors [D27.505.519.389.745.900]
        
        Coronavirus Protease Inhibitors [D27.505.519.389.745.900.250]
        
        HCV NS3-4A Protease Inhibitors [D27.505.519.389.745.900.375]
        
        HIV Protease Inhibitors [D27.505.519.389.745.900.500]

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Therapeutic Uses [D27.505.954]
    - Anti-Infective Agents [D27.505.954.122]
      - Antiviral Agents [D27.505.954.122.388]
        
        Anti-Retroviral Agents [D27.505.954.122.388.077]
        
        Anti-HIV Agents [D27.505.954.122.388.077.088]
        
        CCR5 Receptor Antagonists [D27.505.954.122.388.077.088.104]
        
        HIV Fusion Inhibitors [D27.505.954.122.388.077.088.209]
        
        HIV Integrase Inhibitors [D27.505.954.122.388.077.088.314]
        
        HIV Protease Inhibitors [D27.505.954.122.388.077.088.420]

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Therapeutic Uses [D27.505.954]
    - Anti-Infective Agents [D27.505.954.122]
      - Antiviral Agents [D27.505.954.122.388]
        
        Viral Protease Inhibitors [D27.505.954.122.388.769]
        
        Coronavirus Protease Inhibitors [D27.505.954.122.388.769.250]
        
        HCV NS3-4A Protease Inhibitors [D27.505.954.122.388.769.375]
        
        HIV Protease Inhibitors [D27.505.954.122.388.769.500]

HIV Protease Inhibitors Preferred

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