MeSH Browser

MeSH Heading: HIV Protease
Tree Number(s): D08.811.277.656.074.500.340; D08.811.277.656.300.048.340; D08.811.277.656.979.500; D12.776.964.775.375.545.750; D12.776.964.900.500.625
Unique ID: D016333
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016333
Scope Note: Enzyme of the human immunodeficiency virus that is required for post-translational cleavage of gag and gag-pol precursor polyproteins into functional products needed for viral assembly. HIV protease is an aspartic protease encoded by the amino terminus of the pol gene.
Entry Term(s): HIV Proteinase; HTLV-III Protease; p16 pol gene product, HIV; p16 protease, HIV
Registry Number: EC 3.4.23.-
Previous Indexing: Gene Products, pol (1990); Peptide Peptidohydrolases (1987-1990)
Public MeSH Note: 91
History Note: 91
Entry Combination: antagonists & inhibitors:HIV Protease Inhibitors
Date Established: 1991/01/01
Date of Entry: 1990/06/07
Revision Date: 2020/06/22

Entry Combination: antagonists & inhibitors:HIV Protease Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0024965
Registry Number: EC 3.4.23.-
Scope Note: Enzyme of the human immunodeficiency virus that is required for post-translational cleavage of gag and gag-pol precursor polyproteins into functional products needed for viral assembly. HIV protease is an aspartic protease encoded by the amino terminus of the pol gene.
Terms: HIV Protease Preferred Term
Term UI T048740
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1991); p16 pol gene product, HIV
Term UI T685988
Date11/14/2006
LexicalTag ABX
ThesaurusID NLM (2008); p16 protease, HIV
Term UI T685987
Date11/14/2006
LexicalTag ABX
ThesaurusID NLM (2008); HIV Proteinase
Term UI T048741
Date04/19/1990
LexicalTag ACR
ThesaurusID NLM (1991); HTLV-III Protease
Term UI T048742
Date05/01/1990
LexicalTag ABX
ThesaurusID NLM (1991)

HIV Protease MeSH Descriptor Data 2024