Because of a lapse in government funding, the information on this
website may not be up to date, transactions submitted via the
website may not be processed, and the agency may not be able to
respond to inquiries until appropriations are enacted. The NIH
Clinical Center (the research hospital of NIH) is open. For more
details about its operating status, please visit
cc.nih.gov. Updates
regarding government operating status and resumption of normal
operations can be found at
opm.gov.
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
Entry Term(s)
Angiotensin-Forming Enzyme
Angiotensinogenase
Big Renin
Cryorenin
Inactive Renin
Pre-Prorenin
Preprorenin
Prorenin
Registry Numbers
EC 3.4.23.15
EC 3.4.23.-
EC 3.4.23.-
Related Numbers
80965-96-4
Public MeSH Note
1963; PRORENIN was listed under ENZYME PRECUSORS & RENIN 1977-2003; PREPRORENIN was listed under ENZYME PRECUSORS & RENIN 1980-2003
History Note
1963; for PRORENIN use RENIN (NM) 1977-2003, for PREPRORENIN use RENIN (NM) 1980-2003
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.