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Proprotein Convertase 5 MeSH Descriptor Data 2022


MeSH Heading
Proprotein Convertase 5
Tree Number(s)
D08.811.277.656.300.760.648
D08.811.277.656.837.625
D08.811.277.656.959.350.648
Unique ID
D045702
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D045702
Scope Note
A serine endopeptidase found primarily in the EXTRACELLULAR MATRIX. It has specificity for cleavage of a variety of substrates including PRORENIN, pro-membrane type-1 matrix metalloproteinase, and NEURAL CELL ADHESION MOLECULE L1.
Entry Term(s)
Endoprotease PC6
PC5 Proprotein Convertase
PC5 Protein
PC5A Proprotein Convertase
PC5B Preprotein Convertase
PC6 Endoprotease
PC6 Protein
PC6A Proprotein Convertase
Prohormone Convertase PC-6
Prohormone Convertase PC5
Prohormone Convertase, PC5
Prohormone Convertase-6
SPC6
Registry Number
EC 3.4.21.-
Previous Indexing
Serine Endopeptidases (1993-2003)
Subtilisins (1998-2003)
Public MeSH Note
2004; PC5 PROPROTEIN CONVERTASE (now PREPROTEIN CONVERTASE 5) was indexed under SERINE ENDOPEPTIDASES 1993-1997 & SUBTILISINS 1998-2003
History Note
2004; use PREPROTEIN CONVERTASE 5 (NM) 1993-2003; for PC6 ENDOPROTEASE use PREPROTEIN CONVERTASE 5 (NM) 1993-2003
Date Established
2004/01/01
Date of Entry
2003/07/09
Revision Date
2016/06/28
Proprotein Convertase 5 Preferred
PC5B Preprotein Convertase Narrower
PC6A Proprotein Convertase Narrower
PC5A Proprotein Convertase Narrower
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