MeSH Browser

MeSH Heading: Factor Xa
Tree Number(s): D08.811.277.656.300.760.315; D08.811.277.656.959.350.315; D12.776.124.125.400.315; D23.119.400.315
Unique ID: D015951
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015951
Scope Note: Activated form of factor X that participates in both the intrinsic and extrinsic pathways of blood coagulation. It catalyzes the conversion of prothrombin to thrombin in conjunction with other cofactors.
Entry Term(s): Activated Factor X; Autoprothrombin C; Blood Coagulation Factor X, Activated; Coagulation Factor Xa; Factor 10A; Factor Ten A; Factor X, Activated; Thrombokinase
Registry Numbers: EC 3.4.21.6
Previous Indexing: Factor X (1970-1989); Serine Proteinases (1988-1989)
See Also: Coagulants
Public MeSH Note: 90
History Note: 90
Entry Combination: antagonists & inhibitors:Factor Xa Inhibitors; deficiency:Factor X Deficiency
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2019/05/30

Entry Combination: antagonists & inhibitors:Factor Xa Inhibitors; deficiency:Factor X Deficiency
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Serine Endopeptidases [D08.811.277.656.300.760]
        
        Acrosin [D08.811.277.656.300.760.030]
        
        Cathepsin G [D08.811.277.656.300.760.066]
        
        Chymases [D08.811.277.656.300.760.103]
        
        Chymotrypsin [D08.811.277.656.300.760.176]
        
        Complement Factor B [D08.811.277.656.300.760.198]
        
        Complement Factor D [D08.811.277.656.300.760.200]
        
        Complement Factor I [D08.811.277.656.300.760.210]
        
        Endopeptidase K [D08.811.277.656.300.760.247]
        
        Enteropeptidase [D08.811.277.656.300.760.284]
        
        Factor VIIa [D08.811.277.656.300.760.300]
        
        Factor IXa [D08.811.277.656.300.760.310]
        
        Factor Xa [D08.811.277.656.300.760.315]
        
        Factor XIa [D08.811.277.656.300.760.320]
        
        Factor XIIa [D08.811.277.656.300.760.324]
        
        Fibrinolysin [D08.811.277.656.300.760.330]
        
        Furin [D08.811.277.656.300.760.353]
        
        Granzymes [D08.811.277.656.300.760.397]
        
        High-Temperature Requirement A Serine Peptidase 1 [D08.811.277.656.300.760.420]
        
        High-Temperature Requirement A Serine Peptidase 2 [D08.811.277.656.300.760.431]
        
        Kallikreins [D08.811.277.656.300.760.442]
        
        Lactoferrin [D08.811.277.656.300.760.471]
        
        Mannose-Binding Protein-Associated Serine Proteases [D08.811.277.656.300.760.501]
        
        Myeloblastin [D08.811.277.656.300.760.530]
        
        Pancreatic Elastase [D08.811.277.656.300.760.560]
        
        Plasminogen Activators [D08.811.277.656.300.760.635]
        
        Prolyl Oligopeptidases [D08.811.277.656.300.760.637]
        
        Pronase [D08.811.277.656.300.760.638]
        
        Proprotein Convertase 1 [D08.811.277.656.300.760.640]
        
        Proprotein Convertase 2 [D08.811.277.656.300.760.646]
        
        Proprotein Convertase 5 [D08.811.277.656.300.760.648]
        
        Proprotein Convertase 9 [D08.811.277.656.300.760.718]
        
        Reelin Protein [D08.811.277.656.300.760.753]
        
        Subtilisins [D08.811.277.656.300.760.787]
        
        Thrombin [D08.811.277.656.300.760.855]
        
        Tissue Plasminogen Activator [D08.811.277.656.300.760.875]
        
        Trypsin [D08.811.277.656.300.760.895]
        
        Tryptases [D08.811.277.656.300.760.902]
        
        Urokinase-Type Plasminogen Activator [D08.811.277.656.300.760.910]
        
        Venombin A [D08.811.277.656.300.760.955]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Serine Proteases [D08.811.277.656.959]
        
        Serine Endopeptidases [D08.811.277.656.959.350]
        
        Acrosin [D08.811.277.656.959.350.030]
        
        Cathepsin G [D08.811.277.656.959.350.066]
        
        Chymases [D08.811.277.656.959.350.103]
        
        Chymotrypsin [D08.811.277.656.959.350.176]
        
        Complement Factor B [D08.811.277.656.959.350.198]
        
        Complement Factor D [D08.811.277.656.959.350.200]
        
        Complement Factor I [D08.811.277.656.959.350.210]
        
        Endopeptidase K [D08.811.277.656.959.350.247]
        
        Enteropeptidase [D08.811.277.656.959.350.284]
        
        Factor VIIa [D08.811.277.656.959.350.300]
        
        Factor IXa [D08.811.277.656.959.350.310]
        
        Factor Xa [D08.811.277.656.959.350.315]
        
        Factor XIa [D08.811.277.656.959.350.320]
        
        Factor XIIa [D08.811.277.656.959.350.324]
        
        Fibrinolysin [D08.811.277.656.959.350.330]
        
        Furin [D08.811.277.656.959.350.353]
        
        Granzymes [D08.811.277.656.959.350.397]
        
        High-Temperature Requirement A Serine Peptidase 1 [D08.811.277.656.959.350.420]
        
        High-Temperature Requirement A Serine Peptidase 2 [D08.811.277.656.959.350.431]
        
        Kallikreins [D08.811.277.656.959.350.442]
        
        Lactoferrin [D08.811.277.656.959.350.471]
        
        Mannose-Binding Protein-Associated Serine Proteases [D08.811.277.656.959.350.501]
        
        Myeloblastin [D08.811.277.656.959.350.530]
        
        Pancreatic Elastase [D08.811.277.656.959.350.560]
        
        Plasminogen Activators [D08.811.277.656.959.350.635]
        
        Pronase [D08.811.277.656.959.350.638]
        
        Proprotein Convertase 1 [D08.811.277.656.959.350.640]
        
        Proprotein Convertase 2 [D08.811.277.656.959.350.646]
        
        Proprotein Convertase 5 [D08.811.277.656.959.350.648]
        
        Proprotein Convertase 9 [D08.811.277.656.959.350.718]
        
        Reelin Protein [D08.811.277.656.959.350.753]
        
        Subtilisins [D08.811.277.656.959.350.787]
        
        Thrombin [D08.811.277.656.959.350.855]
        
        Tissue Plasminogen Activator [D08.811.277.656.959.350.875]
        
        Trypsin [D08.811.277.656.959.350.895]
        
        Tryptases [D08.811.277.656.959.350.902]
        
        Urokinase-Type Plasminogen Activator [D08.811.277.656.959.350.910]
        
        Venombin A [D08.811.277.656.959.350.955]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Blood Coagulation Factors [D12.776.124.125]
      - Factor X [D12.776.124.125.400]
        
        Factor Xa [D12.776.124.125.400.315]

Biological Factors [D23]
- Blood Coagulation Factors [D23.119]
  - Factor X [D23.119.400]
    - Factor Xa [D23.119.400.315]

Factor Xa Preferred

Concept UI: M0024399
Registry Numbers: EC 3.4.21.6
Scope Note: Activated form of factor X that participates in both the intrinsic and extrinsic pathways of blood coagulation. It catalyzes the conversion of prothrombin to thrombin in conjunction with other cofactors.
Terms: Factor Xa Preferred Term
Term UI T047348
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1990); Factor Ten A
Term UI T000913560
Date01/04/2017
LexicalTag NON
ThesaurusID NLM (2018); Activated Factor X
Term UI T047344
Date04/24/1989
LexicalTag NON
ThesaurusID NLM (1990); Factor X, Activated
Term UI T047345
Date05/17/1989
LexicalTag NON
ThesaurusID NLM (1990); Autoprothrombin C
Term UI T047346
Date04/24/1989
LexicalTag NON
ThesaurusID NLM (1990); Blood Coagulation Factor X, Activated
Term UI T047347
Date05/17/1989
LexicalTag NON
ThesaurusID NLM (1990); Thrombokinase
Term UI T047349
Date04/24/1989
LexicalTag NON
ThesaurusID NLM (1990); Factor 10A
Term UI T000913559
Date01/04/2017
LexicalTag NON
ThesaurusID NLM (2018); Coagulation Factor Xa
Term UI T047350
Date07/31/1996
LexicalTag NON
ThesaurusID NLM (1998)

Factor Xa MeSH Descriptor Data 2025