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Complement Factor D MeSH Descriptor Data 2022


MeSH Heading
Complement Factor D
Tree Number(s)
D08.811.277.300.450
D08.811.277.656.300.760.200
D08.811.277.656.959.350.200
D12.776.124.486.274.045.450
Unique ID
D011416
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011416
Annotation
see SCR for organism-specific terms
Scope Note
A serum protein which is important in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound COMPLEMENT FACTOR B to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE.
Entry Term(s)
28 kDa Protein, Adipocyte
Adipsin
C3 Convertase Activator
C3 Proactivator Convertase
C3PA Convertase
C3PAse
Complement Protein D
D Component of Complement
Factor D
GBGase
Proactivator Convertase
Properdin Factor D
Pharm Action
Immunologic Factors
Registry Number
EC 3.4.21.46
Previous Indexing
Enzyme Precursors (1966-1977)
Properdin (1966-1977)
Serum Globulins (1970-1977)
Public MeSH Note
1999; see PROPERDIN FACTOR D 1991-1998, see COMPLEMENT ACTIVATING ENZYMES 1978-1990; ADIPSIN was indexed under SERINE ENDOPEPTIDASES 1987-2005
History Note
1999 (1978)
Date Established
1991/01/01
Date of Entry
1977/05/20
Revision Date
2009/07/06
Complement Factor D Preferred
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