MeSH Browser

MeSH Heading: Complement C3 Convertase, Alternative Pathway
Tree Number(s): D12.776.124.486.274.045.387.500.374
Unique ID: D051561
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051561
Scope Note: A serine protease that is the complex of COMPLEMENT C3B and COMPLEMENT FACTOR BB. It cleaves multiple COMPLEMENT C3 into COMPLEMENT C3A (anaphylatoxin) and COMPLEMENT C3B in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY.
Entry Term(s): Alternative Pathway C3 Convertase; C3 Convertase (C3bBb); C3 Convertase, Alternative Pathway; CVFBb; Complement 3 Convertase, Alternative Pathway; Complement 3b-Associated Factor B-fragment Bb; Complement C3 Convertase, CVFBb
Pharm Action: Immunologic Factors
Related Numbers: EC 3.4.21.47
Previous Indexing: Complement C3 (1976-2005); Esterases (1976-2005)
Public MeSH Note: 2006; was indexed under COMPLEMENT 3B 1989-2005; for CVFBB see COMPLEMENT FACTOR B 1985-2005
History Note: 2006 (1989); for CVFBB use COMPLEMENT FACTOR B 1985-2005
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2006/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Complement C3 Convertase, Alternative Pathway MeSH Descriptor Data 2024