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Complement C3b MeSH Descriptor Data 2022


MeSH Heading
Complement C3b
Tree Number(s)
D12.776.124.486.274.250.260
Unique ID
D003179
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003179
Annotation
/antag: consider COMPLEMENT C3B INACTIVATOR PROTEINS
Scope Note
The larger fragment generated from the cleavage of COMPLEMENT C3 by C3 CONVERTASE. It is a constituent of the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb), and COMPLEMENT C5 CONVERTASES in both the classical (C4b2a3b) and the alternative (C3bBb3b) pathway. C3b participates in IMMUNE ADHERENCE REACTION and enhances PHAGOCYTOSIS. It can be inactivated (iC3b) or cleaved by various proteases to yield fragments such as COMPLEMENT C3C; COMPLEMENT C3D; C3e; C3f; and C3g.
Entry Term(s)
C3b Complement
C3bi
Complement 3b
Complement Component 3b
Inactivated C3b
iC3b
Pharm Action
Immunologic Factors
Registry Number
80295-43-8
CAS Type 1 Name
Complement C3b
Previous Indexing
Complement (1968-1974)
Complement 3 (1975-1977)
See Also
Receptors, Complement 3b
Public MeSH Note
2006; see COMPLEMENT 3B 1978-2005
History Note
2006 (1978)
Date Established
1978/01/01
Date of Entry
1977/05/17
Revision Date
2013/07/09
Complement C3b Preferred
Inactivated C3b Narrower
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