MeSH Browser

MeSH Heading: Complement C3b
Tree Number(s): D12.776.124.486.274.250.260
Unique ID: D003179
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D003179
Annotation: /antag: consider COMPLEMENT C3B INACTIVATOR PROTEINS
Scope Note: The larger fragment generated from the cleavage of COMPLEMENT C3 by C3 CONVERTASE. It is a constituent of the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb), and COMPLEMENT C5 CONVERTASES in both the classical (C4b2a3b) and the alternative (C3bBb3b) pathway. C3b participates in IMMUNE ADHERENCE REACTION and enhances PHAGOCYTOSIS. It can be inactivated (iC3b) or cleaved by various proteases to yield fragments such as COMPLEMENT C3C; COMPLEMENT C3D; C3e; C3f; and C3g.
Entry Term(s): C3b Complement; C3bi; Complement 3b; Complement Component 3b; Inactivated C3b; iC3b
Pharm Action: Immunologic Factors
Registry Number: 80295-43-8
CAS Type 1 Name: Complement C3b
Previous Indexing: Complement (1968-1974); Complement 3 (1975-1977)
See Also: Receptors, Complement 3b
Public MeSH Note: 2006; see COMPLEMENT 3B 1978-2005
History Note: 2006 (1978)
Date Established: 1978/01/01
Date of Entry: 1977/05/17
Revision Date: 2013/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0004932
Registry Number: 80295-43-8
Scope Note: The larger fragment generated from the cleavage of COMPLEMENT C3 by C3 CONVERTASE. It is a constituent of the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb), and COMPLEMENT C5 CONVERTASES in both the classical (C4b2a3b) and the alternative (C3bBb3b) pathway. C3b participates in IMMUNE ADHERENCE REACTION and enhances PHAGOCYTOSIS. It can be inactivated (iC3b) or cleaved by various proteases to yield fragments such as COMPLEMENT C3C; COMPLEMENT C3D; C3e; C3f; and C3g.
Terms: Complement C3b Preferred Term
Term UI T623740
Date12/13/2004
LexicalTag NON
ThesaurusID NLM (2006); Complement Component 3b
Term UI T623741
Date12/13/2004
LexicalTag NON
ThesaurusID NLM (2006); C3b Complement
Term UI T631384
Date02/23/2005
LexicalTag NON
ThesaurusID NLM (2006); Complement 3b
Term UI T009285
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1978)

Complement C3b MeSH Descriptor Data 2024