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Complement C3a MeSH Descriptor Data 2022


MeSH Heading
Complement C3a
Tree Number(s)
D12.776.124.486.274.024.250
D12.776.124.486.274.250.250
Unique ID
D015926
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015926
Scope Note
The smaller fragment generated from the cleavage of complement C3 by C3 CONVERTASE. C3a, a 77-amino acid peptide, is a mediator of local inflammatory process. It induces smooth MUSCLE CONTRACTION, and HISTAMINE RELEASE from MAST CELLS and LEUKOCYTES. C3a is considered an anaphylatoxin along with COMPLEMENT C4A; COMPLEMENT C5A; and COMPLEMENT C5A, DES-ARGININE.
Entry Term(s)
C3a Complement
Complement 3a
Complement Component 3a
Pharm Action
Immunologic Factors
Registry Number
80295-42-7
CAS Type 1 Name
Complement C3a
Previous Indexing
Anaphylatoxins (1977-1989)
Complement (1967-1976)
Complement 3 (1975-1989)
Public MeSH Note
2006; see COMPLEMENT 3A 1990-2005
History Note
2006 (1990)
Date Established
1990/01/01
Date of Entry
1989/07/14
Revision Date
2013/07/09
Complement C3a Preferred
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