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Complement C3a MeSH Descriptor Data 2024

MeSH Heading
Complement C3a
Tree Number(s)
Unique ID
RDF Unique Identifier
Scope Note
The smaller fragment generated from the cleavage of complement C3 by C3 CONVERTASE. C3a, a 77-amino acid peptide, is a mediator of local inflammatory process. It induces smooth MUSCLE CONTRACTION, and HISTAMINE RELEASE from MAST CELLS and LEUKOCYTES. C3a is considered an anaphylatoxin along with COMPLEMENT C4A; COMPLEMENT C5A; and COMPLEMENT C5A, DES-ARGININE.
Entry Term(s)
C3a Complement
Complement 3a
Complement Component 3a
Pharm Action
Immunologic Factors
CAS Type 1 Name
Complement C3a
Previous Indexing
Anaphylatoxins (1977-1989)
Complement (1967-1976)
Complement 3 (1975-1989)
Public MeSH Note
2006; see COMPLEMENT 3A 1990-2005
History Note
2006 (1990)
Date Established
Date of Entry
Revision Date
Complement C3a Preferred
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