MeSH Browser

MeSH Heading: Complement C3a
Tree Number(s): D12.776.124.486.274.024.250; D12.776.124.486.274.250.250
Unique ID: D015926
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015926
Scope Note: The smaller fragment generated from the cleavage of complement C3 by C3 CONVERTASE. C3a, a 77-amino acid peptide, is a mediator of local inflammatory process. It induces smooth MUSCLE CONTRACTION, and HISTAMINE RELEASE from MAST CELLS and LEUKOCYTES. C3a is considered an anaphylatoxin along with COMPLEMENT C4A; COMPLEMENT C5A; and COMPLEMENT C5A, DES-ARGININE.
Entry Term(s): C3a Complement; Complement 3a; Complement Component 3a
Pharm Action: Immunologic Factors
CAS Type 1 Name: Complement C3a
Previous Indexing: Anaphylatoxins (1977-1989); Complement (1967-1976); Complement 3 (1975-1989)
Public MeSH Note: 2006; see COMPLEMENT 3A 1990-2005
History Note: 2006 (1990)
Date Established: 1990/01/01
Date of Entry: 1989/07/14
Revision Date: 2013/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0024371
Scope Note: The smaller fragment generated from the cleavage of complement C3 by C3 CONVERTASE. C3a, a 77-amino acid peptide, is a mediator of local inflammatory process. It induces smooth MUSCLE CONTRACTION, and HISTAMINE RELEASE from MAST CELLS and LEUKOCYTES. C3a is considered an anaphylatoxin along with COMPLEMENT C4A; COMPLEMENT C5A; and COMPLEMENT C5A, DES-ARGININE.
Terms: Complement C3a Preferred Term
Term UI T623661
Date12/13/2004
LexicalTag NON
ThesaurusID NLM (2006); C3a Complement
Term UI T631383
Date02/23/2005
LexicalTag NON
ThesaurusID NLM (2006); Complement 3a
Term UI T047249
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1990); Complement Component 3a
Term UI T623662
Date12/13/2004
LexicalTag NON
ThesaurusID NLM (2006)

Complement C3a MeSH Descriptor Data 2024