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Anaphylatoxins MeSH Descriptor Data 2022


MeSH Heading
Anaphylatoxins
Tree Number(s)
D12.776.124.486.274.024
Unique ID
D000706
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000706
Scope Note
Serum peptides derived from certain cleaved COMPLEMENT PROTEINS during COMPLEMENT ACTIVATION. They induce smooth MUSCLE CONTRACTION; mast cell HISTAMINE RELEASE; PLATELET AGGREGATION; and act as mediators of the local inflammatory process. The order of anaphylatoxin activity from the strongest to the weakest is C5a, C3a, C4a, and C5a des-arginine.
Entry Term(s)
Anaphylatoxin
Pharm Action
Immunologic Factors
Registry Number
0
NLM Classification #
QU 68
Previous Indexing
Complement (1968-1976)
Peptide Fragments (1974-1976)
Peptides (1966-1976)
specific complement (1975-1976)
Public MeSH Note
90; was see under PEPTIDES 1977-89
History Note
90(77); was see under PEPTIDES 1977-89
Date Established
1990/01/01
Date of Entry
1976/05/19
Revision Date
2018/07/02
Anaphylatoxins Preferred
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