MeSH Browser

MeSH Heading: Anaphylatoxins
Tree Number(s): D12.776.124.486.274.024
Unique ID: D000706
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000706
Scope Note: Serum peptides derived from certain cleaved COMPLEMENT PROTEINS during COMPLEMENT ACTIVATION. They induce smooth MUSCLE CONTRACTION; mast cell HISTAMINE RELEASE; PLATELET AGGREGATION; and act as mediators of the local inflammatory process. The order of anaphylatoxin activity from the strongest to the weakest is C5a, C3a, C4a, and C5a des-arginine.
Entry Term(s): Anaphylatoxin
Pharm Action: Immunologic Factors
NLM Classification #: QU 68
Previous Indexing: Complement (1968-1976); Peptide Fragments (1974-1976); Peptides (1966-1976); specific complement (1975-1976)
Public MeSH Note: 90; was see under PEPTIDES 1977-89
History Note: 90(77); was see under PEPTIDES 1977-89
Date Established: 1990/01/01
Date of Entry: 1976/05/19
Revision Date: 2018/07/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Anaphylatoxins MeSH Descriptor Data 2024