MeSH Browser

MeSH Heading: Complement C6
Tree Number(s): D12.776.124.486.274.550
Unique ID: D003183
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D003183
Scope Note: A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32 disulfide bonds. C6 is the next complement component to bind to the membrane-bound COMPLEMENT C5B in the assembly of MEMBRANE ATTACK COMPLEX. It is encoded by gene C6.
Entry Term(s): C6 Complement; Complement 6; Complement Component 6
Pharm Action: Immunologic Factors
Previous Indexing: Complement (1968-1974)
Public MeSH Note: 2006; see COMPLEMENT 6 1978-2005, see COMPLEMENT 1975-1977
History Note: 2006 (1975)
Date Established: 1978/01/01
Date of Entry: 1974/11/11
Revision Date: 2005/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0004938
Scope Note: A 105-kDa serum glycoprotein with significant homology to the other late complement components, C7-C9. It is a polypeptide chain cross-linked by 32 disulfide bonds. C6 is the next complement component to bind to the membrane-bound COMPLEMENT C5B in the assembly of MEMBRANE ATTACK COMPLEX. It is encoded by gene C6.
Terms: Complement C6 Preferred Term
Term UI T624014
Date12/14/2004
LexicalTag NON
ThesaurusID NLM (2006); C6 Complement
Term UI T631390
Date02/23/2005
LexicalTag NON
ThesaurusID NLM (2006); Complement 6
Term UI T009298
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Complement Component 6
Term UI T624015
Date12/14/2004
LexicalTag NON
ThesaurusID NLM (2006)

Complement C6 MeSH Descriptor Data 2024