MeSH Browser

MeSH Heading: Complement C5b
Tree Number(s): D12.776.124.486.274.450.625
Unique ID: D050776
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050776
Scope Note: The larger fragment generated from the cleavage of C5 by C5 CONVERTASE that yields COMPLEMENT C5A and C5b (beta chain + alpha' chain, the residual alpha chain, bound by disulfide bond). C5b remains bound to the membrane and initiates the spontaneous assembly of the late complement components to form C5b-8-poly-C9, the MEMBRANE ATTACK COMPLEX.
Entry Term(s): C5b Complement; Complement 5b; Complement Component 5b
Pharm Action: Immunologic Factors
CAS Type 1 Name: Complement C 5b
Public MeSH Note: 2006; COMPLEMENT C5B was indexed under COMPLEMENT 5 1982-2005
History Note: 2006 (1982)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2013/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0105345
Scope Note: The larger fragment generated from the cleavage of C5 by C5 CONVERTASE that yields COMPLEMENT C5A and C5b (beta chain + alpha' chain, the residual alpha chain, bound by disulfide bond). C5b remains bound to the membrane and initiates the spontaneous assembly of the late complement components to form C5b-8-poly-C9, the MEMBRANE ATTACK COMPLEX.
Terms: Complement C5b Preferred Term
Term UI T601215
Date08/02/2004
LexicalTag NON
ThesaurusID NLM (2006); C5b Complement
Term UI T631389
Date02/23/2005
LexicalTag NON
ThesaurusID NLM (2006); Complement 5b
Term UI T135349
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Complement Component 5b
Term UI T623854
Date12/14/2004
LexicalTag NON
ThesaurusID NLM (2006)

Complement C5b MeSH Descriptor Data 2024