- Concept UI
- M0004937
- Registry Number
- 0
- Scope Note
- C5 plays a central role in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C5 is cleaved by C5 CONVERTASE into COMPLEMENT C5A and COMPLEMENT C5B. The smaller fragment C5a is an ANAPHYLATOXIN and mediator of inflammatory process. The major fragment C5b binds to the membrane initiating the spontaneous assembly of the late complement components, C5-C9, into the MEMBRANE ATTACK COMPLEX.
- Terms
-
Complement C5
Preferred Term
Term UI
T623828
Date12/14/2004
LexicalTag
NON
ThesaurusID
NLM (2006)
-
C5 Complement
Term UI
T631387
Date02/23/2005
LexicalTag
NON
ThesaurusID
NLM (2006)
-
Complement 5
Term UI
T009296
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1975)
-
Complement Component 5
Term UI
T623829
Date12/14/2004
LexicalTag
NON
ThesaurusID
NLM (2006)