- Concept UI
- M0024381
- Registry Numbers
- 80295-54-1
- Scope Note
- The minor fragment formed when C5 convertase cleaves C5 into C5a and COMPLEMENT C5B. C5a is a 74-amino-acid glycopeptide with a carboxy-terminal ARGININE that is crucial for its spasmogenic activity. Of all the complement-derived anaphylatoxins, C5a is the most potent in mediating immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE), smooth MUSCLE CONTRACTION; HISTAMINE RELEASE; and migration of LEUKOCYTES to site of INFLAMMATION.
- Terms
-
Complement C5a
Preferred Term
Term UI
T623936
Date12/14/2004
LexicalTag
NON
ThesaurusID
NLM (2006)
-
Complement 5a
Term UI
T047286
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1990)
-
Complement Component 5a
Term UI
T623937
Date12/14/2004
LexicalTag
NON
ThesaurusID
NLM (2006)
-
C5a Complement
Term UI
T631388
Date02/23/2005
LexicalTag
NON
ThesaurusID
NLM (2006)