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Complement C2 MeSH Descriptor Data 2022


MeSH Heading
Complement C2
Tree Number(s)
D12.776.124.486.274.150
Unique ID
D003175
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003175
Scope Note
A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMPLEMENT C2B and COMPLEMENT C2A. C2a, the COOH-terminal fragment containing a SERINE PROTEASE, combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
Entry Term(s)
C2 Complement
Complement 2
Complement Component 2
Pharm Action
Immunologic Factors
Registry Number
0
Previous Indexing
Complement (1968-1974)
Magnesium (1966-1974)
Protein Binding (1966-1974)
Public MeSH Note
2006; see COMPLEMENT 2 1978-2005, see COMPLEMENT 1975-1977
History Note
2006 (1975)
Date Established
1978/01/01
Date of Entry
1974/11/11
Revision Date
2005/06/30
Complement C2 Preferred
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