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Complement C9 MeSH Descriptor Data 2022


MeSH Heading
Complement C9
Tree Number(s)
D12.776.124.486.274.850
Unique ID
D003186
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003186
Scope Note
A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections.
Entry Term(s)
C9 Complement
Complement 9
Complement Component 9
Pharm Action
Immunologic Factors
Registry Number
0
Previous Indexing
Bacteriolysis (1966-1974)
Complement (1968-1974)
Hemolysis (1966-1974)
specific cell
Public MeSH Note
2006; see COMPLEMENT 9 1978-2005, see COMPLEMENT 1975-1977
History Note
2006 (1975)
Date Established
1978/01/01
Date of Entry
1974/11/11
Revision Date
2005/06/30
Complement C9 Preferred
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