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Complement C7 MeSH Descriptor Data 2022


MeSH Heading
Complement C7
Tree Number(s)
D12.776.124.486.274.650
Unique ID
D003184
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003184
Scope Note
A 93-kDa serum glycoprotein encoded by C7 gene. It is a polypeptide chain with 28 disulfide bridges. In the formation of MEMBRANE ATTACK COMPLEX; C7 is the next component to bind the C5b-6 complex forming a trimolecular complex C5b-7 which is lipophilic, resembles an integral membrane protein, and serves as an anchor for the late complement components, C8 and C9.
Entry Term(s)
C7 Complement
Complement 7
Complement Component 7
Pharm Action
Immunologic Factors
Registry Number
0
Previous Indexing
Chemotaxis (1966-1974)
Complement (1968-1974)
Neutrophils (1966-1974)
Public MeSH Note
2006; see COMPLEMENT 7 1978-2005, see COMPLEMENT 1975-1977
History Note
2006 (1975)
Date Established
1978/01/01
Date of Entry
1974/11/11
Revision Date
2005/07/19
Complement C7 Preferred
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