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Granzymes MeSH Descriptor Data 2023


MeSH Heading
Granzymes
Tree Number(s)
D08.811.277.656.300.760.397
D08.811.277.656.959.350.397
Unique ID
D053804
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053804
Scope Note
A family of serine endopeptidases found in the SECRETORY GRANULES of LEUKOCYTES such as CYTOTOXIC T-LYMPHOCYTES and NATURAL KILLER CELLS. When secreted into the intercellular space granzymes act to eliminate transformed and virus-infected host cells.
Entry Term(s)
Cytotoxic Serine Protease B
Cytotoxic T-Lymphocyte Associated 1 Protein
Cytotoxic T-Lymphocyte Proteinase 1
Fragmentin 2
Granzyme
Granzyme A
Granzyme B
Granzyme C
Granzyme K
Granzyme M
Granzyme-3
Granzyme-Like Protein III
Hanukah Factor
NK-Tryptase-2
Natural Killer Cell Granule Tryptase-2
Pharm Action
Cytotoxins
Registry Number
EC 3.4.21.-
Related Numbers
EC 3.4.21.78
Public MeSH Note
2007; GRANZYME A was indexed under SERINE ENDOPEPTIDASES 1986-2006; GRANZYME B was indexed under SERINE ENDOPEPTIDASES 1989-2006; GRANZYME C was indexed under SERINE ENDOPEPTIDASES 1988-2006; GRANZYME M was indexed under SERINE ENDOPEPTIDASES 1999-2006; GRANZYME-LIKE PROTEIN III was indexed under SERINE ENDOPEPTIDASES 1994-2006; GRANZYME K was indexed under SERINE ENDOPEPTIDASES 2003-2006
History Note
2007(1986)
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2009/07/06
Granzymes Preferred
Granzyme M Narrower
Granzyme C Narrower
Granzyme K Narrower
Granzyme A Narrower
Granzyme B Narrower
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