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Urokinase-Type Plasminogen Activator MeSH Descriptor Data 2025
A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES.
Entry Term(s)
Abbokinase
Kidney Plasminogen Activator
Plasminogen Activator, Urokinase-Type
Renokinase
Single-Chain Urokinase-Type Plasminogen Activator
U-PA
U-Plasminogen Activator
Urinary Plasminogen Activator
Urokinase
Registry Numbers
EC 3.4.21.73
0
Related Numbers
9039-53-6
Previous Indexing
Fibrinolytic Agents (1966-1974)
Public MeSH Note
2009; see URINARY PLASMINOGEN ACTIVATOR 2000-2008, see UROKINASE 1984-1999, see PEPTIDE PEPTIDOHYDROLASES 1975-1983, see FIBRINOLYTIC AGENTS 1966-1974, see STREPTODORNASE AND STREPTOKINASE 1963-1965; UROKINASE-TYPE PLASMINOGEN ACTIVATOR was indexed under PLASMINOGEN ACTIVATORS & UROKINASE 1984-1999
A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES.