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Urokinase-Type Plasminogen Activator MeSH Descriptor Data 2022


MeSH Heading
Urokinase-Type Plasminogen Activator
Tree Number(s)
D08.811.277.656.300.760.910
D08.811.277.656.959.350.910
D12.776.124.125.662.884
Unique ID
D014568
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D014568
Scope Note
A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES.
Entry Term(s)
Abbokinase
Kidney Plasminogen Activator
Plasminogen Activator, Urokinase-Type
Renokinase
Single-Chain Urokinase-Type Plasminogen Activator
U-PA
U-Plasminogen Activator
Urinary Plasminogen Activator
Urokinase
Registry Number
EC 3.4.21.73
Related Numbers
9039-53-6
Previous Indexing
Fibrinolytic Agents (1966-1974)
Public MeSH Note
2009; see URINARY PLASMINOGEN ACTIVATOR 2000-2008, see UROKINASE 1984-1999, see PEPTIDE PEPTIDOHYDROLASES 1975-1983, see FIBRINOLYTIC AGENTS 1966-1974, see STREPTODORNASE AND STREPTOKINASE 1963-1965; UROKINASE-TYPE PLASMINOGEN ACTIVATOR was indexed under PLASMINOGEN ACTIVATORS & UROKINASE 1984-1999
History Note
2009(1963)
Date Established
1984/01/01
Date of Entry
1999/01/01
Revision Date
2009/07/06
Urokinase-Type Plasminogen Activator Preferred
Renokinase Narrower
Abbokinase Narrower
Kidney Plasminogen Activator Narrower
Single-Chain Urokinase-Type Plasminogen Activator Narrower
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