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Spironolactone MeSH Descriptor Data 2022


MeSH Heading
Spironolactone
Tree Number(s)
D02.540.679
D04.210.500.745.745.855
Unique ID
D013148
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D013148
Scope Note
A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
Entry Term(s)
Aldactone
Aldactone A
Aquareduct
Duraspiron
Espironolactona Alter
Espironolactona Mundogen
Flumach
Frumikal
Jenaspiron
Novo-Spiroton
Practon
SC-9420
Spiractin
Spiro L.U.T.
Spiro Von Ct
Spirobeta
Spirogamma
Spirolactone
Spirolang
Spirono-Isis
Spironone
Spirospare
Veroshpiron
Verospiron
Verospirone
Pharm Action
Mineralocorticoid Receptor Antagonists
Diuretics
Registry Number
27O7W4T232
Related Numbers
52-01-7
CAS Type 1 Name
Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)-
NLM Classification #
QV 160
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2017/05/24
Spironolactone Preferred
Spiractin Narrower
Spirobeta Narrower
Spirogamma Narrower
Spirolang Narrower
Spirono-Isis Narrower
Spironone Narrower
Spirospare Narrower
Aldactone Narrower
Verospiron Narrower
Aldactone A Narrower
Aquareduct Narrower
Duraspiron Narrower
Espironolactona Alter Narrower
Espironolactona Mundogen Narrower
Flumach Narrower
Frumikal Narrower
Jenaspiron Narrower
Novo-Spiroton Narrower
Practon Narrower
SC-9420 Narrower
Spiro L.U.T. Narrower
Spiro Von Ct Narrower
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