MeSH Browser

MeSH Heading: Zearalenone
Tree Number(s): D02.455.426.559.389.657.852.900; D02.540.950; D23.946.587.989
Unique ID: D015025
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015025
Annotation: a mycotoxin & non-steroidal estrogen; do not confuse with zearalanone (index under ZEARALENONE /‌analogs)
Scope Note: (S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione. One of a group of compounds known under the general designation of resorcylic acid lactones. Cis, trans, dextro and levo forms have been isolated from the fungus Gibberella zeae (formerly Fusarium graminearum). They have estrogenic activity, cause toxicity in livestock as feed contaminant, and have been used as anabolic or estrogen substitutes.
Entry Term(s): F-2 Toxin; F2 Toxin
Pharm Action: Estrogens, Non-Steroidal
Registry Number: 5W827M159J
Related Numbers: 17924-92-4
CAS Type 1 Name: 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-, (S-(E))-
Previous Indexing: Lactones (1966-1974); Resorcinols (1966-1974)
Public MeSH Note: 91; was see under RESORCINOLS 1975-90
History Note: 91(75); was see under RESORCINOLS 1975-90
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0023120
Registry Number: 5W827M159J
Related Numbers: 17924-92-4
Scope Note: (S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione. One of a group of compounds known under the general designation of resorcylic acid lactones. Cis, trans, dextro and levo forms have been isolated from the fungus Gibberella zeae (formerly Fusarium graminearum). They have estrogenic activity, cause toxicity in livestock as feed contaminant, and have been used as anabolic or estrogen substitutes.
Terms: Zearalenone Preferred Term
Term UI T043834
Date01/01/1999
LexicalTag NON
ThesaurusID; F2 Toxin
Term UI T043835
Date05/20/1980
LexicalTag NON
ThesaurusID UNK (19XX); F-2 Toxin
Term UI T043833
Date05/20/1980
LexicalTag NON
ThesaurusID UNK (19XX)

Zearalenone MeSH Descriptor Data 2024