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Amanitins MeSH Descriptor Data 2022


MeSH Heading
Amanitins
Tree Number(s)
D04.345.566.050
D12.644.456.050
D12.644.641.050
D23.946.587.175
Unique ID
D000546
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000546
Annotation
/antag permitted but consider also ANTITOXINS
Scope Note
Cyclic peptides extracted from carpophores of various mushroom species. They are potent inhibitors of RNA polymerases in most eukaryotic species, blocking the production of mRNA and protein synthesis. These peptides are important in the study of transcription. Alpha-amanitin is the main toxin from the species Amanitia phalloides, poisonous if ingested by humans or animals.
Entry Term(s)
Amanitin
Pharm Action
Enzyme Inhibitors
Poisons
Nucleic Acid Synthesis Inhibitors
Registry Number
0
Previous Indexing
Mycotoxins (1974)
Oligopeptides (1974)
Peptides, Cyclic (1974)
Public MeSH Note
75
History Note
75
Date Established
1975/09/01
Date of Entry
1974/11/11
Revision Date
2020/05/27
Amanitins Preferred
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