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5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase MeSH Descriptor Data 2023


MeSH Heading
5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Tree Number(s)
D08.811.913.555.500.645
Unique ID
D013766
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D013766
Annotation
/defic: consider also HOMOCYSTINURIA
Scope Note
An enzyme that catalyzes the formation of methionine by transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine. It requires a cobamide coenzyme. The enzyme can act on mono- or triglutamate derivatives. EC 2.1.1.13.
Entry Term(s)
Methionine Synthase
Methionine Synthetase
Methyltetrahydrofolate Homocysteine Methyltransferase
Tetrahydropteroylglutamate Methyltransferase
Vitamin B12-Dependent Methionine Synthase
Vitamin B12-Independent Methionine Synthase
Registry Number
EC 2.1.1.13
Related Numbers
9033-23-2
CAS Type 1 Name
5-Methyltetrahydropteroyltri-L-glutamate:L-homocysteine S-methyltransferase
Previous Indexing
Methionine (1973-1974)
Methyltransferases (1973-1974)
Tetrahydrofolates (1973-1974)
See Also
Homocystinuria
Public MeSH Note
98; see TETRAHYDROPTEROYLGLUTAMATE METHYLTRANSFERASE 1991-97; see METHYLTRANSFERASES 1975-90
History Note
98(75)
Date Established
1991/01/01
Date of Entry
1974/11/19
Revision Date
2005/06/30
5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase Preferred
Vitamin B12-Independent Methionine Synthase Narrower
Vitamin B12-Dependent Methionine Synthase Narrower
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