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Thymidylate Synthase MeSH Descriptor Data 2022


MeSH Heading
Thymidylate Synthase
Tree Number(s)
D08.811.913.555.500.862
Unique ID
D013940
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D013940
Scope Note
An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of thymidine triphosphate. (From Dorland, 27th ed) EC 2.1.1.45.
Entry Term(s)
Thymidylate Synthetase
Registry Number
EC 2.1.1.45
Related Numbers
9031-61-2
CAS Type 1 Name
5,10-Methylenetetrahydrofolate:dUMP C-methyltransferase
Previous Indexing
Ligases (1966-1970)
Methyltransferases (1971-1972)
Transferases (1969-1972)
Public MeSH Note
1998; see METHYLTRANSFERASES 1975-1985, see THYMIDYLATE SYNTHETASE 1985-1997
History Note
1998; see METHYLTRANSFERASES 1975-1985
Date Established
1986/01/01
Date of Entry
1999/01/01
Revision Date
2019/07/01
Thymidylate Synthase Preferred
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