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Thiotepa MeSH Descriptor Data 2023


MeSH Heading
Thiotepa
Tree Number(s)
D02.705.672.875
D03.383.097.217.935.960
Unique ID
D013852
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D013852
Scope Note
A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Entry Term(s)
AI3-24916
Girostan
NSC-6396
Tespa
Tespamin
Thio-Tepa
Thiophosphamide
Triethylenethiophosphoramide
Tris(1-aziridinyl)phosphine Sulfide
Pharm Action
Antineoplastic Agents, Alkylating
Myeloablative Agonists
Registry Number
905Z5W3GKH
Related Numbers
52-24-4
CAS Type 1 Name
Aziridine, 1,1',1''-phosphinothioylidynetris-
NLM Classification #
QV 269
Public MeSH Note
92; was THIO-TEPA 1963-91; THIOTEPA was see THIO-TEPA 1977-91
Online Note
use THIOTEPA to search THIO-TEPA 1966-91
History Note
92; was THIO-TEPA 1963-91; THIOTEPA was see THIO-TEPA 1977-91
Date Established
1992/01/01
Date of Entry
1999/01/01
Revision Date
2016/06/01
Thiotepa Preferred
Tespamin Narrower
NSC-6396 Narrower
Tespa Narrower
AI3-24916 Narrower
Girostan Narrower
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