MeSH Browser

MeSH Heading: 4-Nitroquinoline-1-oxide
Tree Number(s): D02.640.820.600; D03.633.100.810.470.450; D03.661.243.500
Unique ID: D015112
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015112
Scope Note: A potent mutagen and carcinogen. This compound and its metabolite 4-HYDROXYAMINOQUINOLINE-1-OXIDE bind to nucleic acids. It inactivates bacteria but not bacteriophage.
Entry Term(s): 4-Nitroquinoline-N-oxide
Pharm Action: Carcinogens
Mutagens
CAS Type 1 Name: Quinoline, 4-nitro-, 1-oxide
Previous Indexing: Cyclic N-Oxides (1972-1974); Nitro Compounds (1972-1974); Quinolines (1970-1974)
Public MeSH Note: 91; was see under NITROQUINOLINES 1975-90
History Note: 91(75); was see under NITROQUINOLINES 1975-90
Date Established: 1991/01/01
Date of Entry: 1974/11/14
Revision Date: 2016/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analogs & derivatives (AA)

analysis (AN)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

4-Nitroquinoline-1-oxide MeSH Descriptor Data 2024