NLM Logo

Deoxyribonucleases, Type I Site-Specific MeSH Descriptor Data 2022


MeSH Heading
Deoxyribonucleases, Type I Site-Specific
Tree Number(s)
D08.811.150.280.250
D08.811.277.352.335.350.300.250
D08.811.277.352.355.325.300.250
Unique ID
D015253
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015253
Scope Note
Enzyme systems containing three different subunits and requiring ATP, S-adenosylmethionine, and magnesium for endonucleolytic activity to give random double-stranded fragments with terminal 5'-phosphates. They function also as DNA-dependent ATPases and modification methylases, catalyzing the reactions of EC 2.1.1.72 and EC 2.1.1.73 with similar site-specificity. The systems recognize specific short DNA sequences and cleave at sites remote from the recognition sequence. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.3.
Entry Version
DNASE SS I
Entry Term(s)
DNA Restriction Enzymes, Type I
DNase, Site Specific, Type I
DNase, Site-Specific, Type I
Deoxyribonucleases, Type I, Site Specific
Deoxyribonucleases, Type I, Site-Specific
Restriction Endonucleases, Type I
Site-Specific DNase, Type I
Type I Restriction Enzymes
Type I Site Specific DNase
Type I Site Specific Deoxyribonucleases
Type I Site-Specific DNase
Type I Site-Specific Deoxyribonucleases
Registry Number
EC 3.1.21.3
Previous Indexing
DNA Restriction Enzymes (1978-1988)
Public MeSH Note
89
History Note
89
Date Established
1989/01/01
Date of Entry
1988/05/17
Revision Date
2003/07/09
Deoxyribonucleases, Type I Site-Specific Preferred
page delivered in 0.154s