MeSH Browser

MeSH Heading: RNA Probes
Tree Number(s): D13.444.600.723; D27.505.259.750.600.825; D27.720.470.530.600.825
Unique ID: D015347
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015347
Annotation: usually no qualif: /‌drug eff /‌ultrastruct permitted
Scope Note: RNA, usually prepared by transcription from cloned DNA, which complements a specific mRNA or DNA and is generally used for studies of virus genes, distribution of specific RNA in tissues and cells, integration of viral DNA into genomes, transcription, etc. Whereas DNA PROBES are preferred for use at a more macroscopic level for detection of the presence of DNA/RNA from specific species or subspecies, RNA probes are preferred for genetic studies. Conventional labels for the RNA probe include radioisotope labels 32P and 125I and the chemical label biotin. RNA probes may be further divided by category into plus-sense RNA probes, minus-sense RNA probes, and antisense RNA probes.
Entry Term(s): Gene Probes, RNA; RNA Probe
Registry Numbers: 0
Previous Indexing: Nucleic Acid Hybridization (1972-1988); RNA, Messenger (1972-1988)
Public MeSH Note: 89
History Note: 89
Date Established: 1989/01/01
Date of Entry: 1988/06/02
Revision Date: 2020/06/25

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0023632
Registry Numbers: 0
Scope Note: RNA, usually prepared by transcription from cloned DNA, which complements a specific mRNA or DNA and is generally used for studies of virus genes, distribution of specific RNA in tissues and cells, integration of viral DNA into genomes, transcription, etc. Whereas DNA PROBES are preferred for use at a more macroscopic level for detection of the presence of DNA/RNA from specific species or subspecies, RNA probes are preferred for genetic studies. Conventional labels for the RNA probe include radioisotope labels 32P and 125I and the chemical label biotin. RNA probes may be further divided by category into plus-sense RNA probes, minus-sense RNA probes, and antisense RNA probes.
Terms: RNA Probes Preferred Term
Term UI T045172
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1989); Gene Probes, RNA
Term UI T045171
Date06/02/1988
LexicalTag NON
ThesaurusID UNK (19XX); RNA Probe
Term UI T001083377
Date06/23/2020
LexicalTag NON
ThesaurusID NLM (2021)

RNA Probes MeSH Descriptor Data 2024