MeSH Browser

MeSH Heading: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Tree Number(s): D03.383.725.450
Unique ID: D015632
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015632
Scope Note: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
Entry Term(s): MPTP; N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Pharm Action: Neurotoxins
Dopamine Agents
Related Numbers: 28289-54-5
CAS Type 1 Name: Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-phenyl-
Previous Indexing: Pyridines (1966-1989)
Public MeSH Note: 90
History Note: 90
Entry Combination: poisoning:MPTP Poisoning; toxicity:MPTP Poisoning
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2016/05/27

Entry Combination: poisoning:MPTP Poisoning; toxicity:MPTP Poisoning
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

urine (UR)

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine MeSH Descriptor Data 2024