MeSH Browser

MeSH Heading: Metyrapone
Tree Number(s): D03.383.725.463
Unique ID: D008797
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008797
Scope Note: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
Entry Term(s): Methbipyranone; Methopyrapone; Metopiron; Metopirone; Métopirone; SU 4885
Pharm Action: Antimetabolites
Enzyme Inhibitors
Registry Numbers: ZS9KD92H6V; 0
Related Numbers: 54-36-4
CAS Type 1 Name: 1-Propanone, 2-methyl-1,2-di-3-pyridinyl-
Public MeSH Note: 66
History Note: 66(64)
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Metyrapone MeSH Descriptor Data 2025